SARS-COV-2 OMICRON BA.2.75 VARIANT MAY BE MUCH MORE INFECTIVE THAN PREEXISTING VARIANTS BASED ON IN SILICO MODEL

SARS-CoV-2 Omicron BA.2.75 Variant May Be Much More Infective than Preexisting Variants Based on In Silico Model

Previously, we developed a mathematical model via molecular simulation analysis to predict the infectivity of six SARS-CoV-2 variants.In this report, we aimed to predict the relative risk of the recent new variants of SARS-CoV-2 based on our previous research.We subjected Omicron BA.4/5 and BA.2.75 variants of SARS-CoV-2 to the analysis to determin

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Experimental Investigation into Limit Void Ratio Characteristics of Calcareous Sands considering Various Factors

Relative density is an important index affecting the mechanical behaviors of nemacor maxx calcareous sands.The dense sands present softening strength, whereas the loose sands exhibit hardening strength.Furthermore, the relative density is determined based on the maximum and minimum void ratios obtained by using the maximum and minimum dry density t

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Plants know where it hurts: root and shoot jasmonic acid induction elicit differential responses in Brassica oleracea.

Plants respond to herbivore attack by rapidly inducing defenses that are mainly regulated by jasmonic acid (JA).Due to the systemic nature of induced defenses, attack by root herbivores can also result in a shoot response and vice versa, causing interactions between above- and belowground herbivores.However, little is known about the molecular mech

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Amino acid polymorphisms in human histocompatibility leukocyte antigen class II and proinsulin epitope have impacts on type 1 diabetes mellitus induced by immune-checkpoint inhibitors

IntroductionImmune-checkpoint inhibitors are effective in various advanced cancers.Type 1 diabetes mellitus induced by them (ICI-T1DM) is a serious complication requiring prompt insulin treatment, but the immunological mechanism behind it is unclear.MethodsWe examined amino acid polymorphisms in human histocompatibility leukocyte antigen (HLA) mole

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